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HyLabsProductsResearchCustom Oligos, Genes and PeptidesMETABION- CUSTOM OLIGOSCustom DNA Oligo

Product: Custom DNA Oligo

Our service at a glance:

  • You order your desired DNA oligos with the possibility of choosing between a seasoned selection of modifications (all DNA oligos have terminal hydroxyl groups at both ends);
  • For further assistance with your order, you can contact us oligo@hylabs.co.il
  • If you order within 6 pm CET/CEST, we start processing your order on the same day;
  • You will receive your DNA oligos dry, unless otherwise specified;
  • Synthesis of large-scale DNA oligos is also available. 
  • All our oligos are subject to strict quality control by mass spectrometry.

Our standard custom DNA Oligos – Portfolio

  • 4 synthesis scales with guaranteed yield expressed in ODs:
Yield Guarantee (OD₂₆₀) *
Synthesis Scale Desalted OPC Purified HPLC Purified
unmodified single modified unmodified single modified unmodified single modified
0.02 µmol 3 3 1 n.a. 1 1
0.04 µmol 5 5 3 n.a. 2.5 2
0.2 µmol 16 12 15 n.a. 8 5
1 µmol 80 50 n.a. n.a. 35 15

*The yield guarantee is calculated for unmodified oligonucleotides (20mers).

  • 0.02 µmol scale only available for oligos up to 33 bases;
  • OPC purification only available for unmodified oligos up to 40 bases;
  • Delivery in single tubes, shipping condition dry;
  • Comprehensive pricing scheme;
  • An extended standard selection of single modifications (5´, internal, 3´). See tables below:

Fluorescent Modifications

Type Position Spectrum Maxima
  5′ 3′ internal Abs Em
Atto 390 ✓ ✓ ✓ 390 476
Atto 425 ✓ ✓ ✓ 439 485
Atto 465 ✓ ✓ ✓ 453 506
6-Fam ✓ ✓ ✓ 495 520
Atto 495 ✓ ✓ ✓ 498 526
Atto 488 ✓ ✓ ✓ 500 520
Tet ✓ ✓ ✓ 521 542
Atto 520 ✓ ✓ ✓ 517 538
Atto 430LS ✓ ✓ ✓ 436 545
Joe ✓ ✓   520 545
Yakima Yellow® ✓     530 550
Atto 532 ✓ ✓ ✓ 532 552
Hex ✓ ✓ ✓ 533 559
Atto Rho6G ✓ ✓ ✓ 533 557
Atto 550 ✓ ✓ ✓ 554 576
Tamra ✓ ✓ ✓ 543 575
Cy3 ✓ ✓ ✓ 552 565
Cy3B ✓ ✓ ✓ 559 570
DY510XL ✓ ✓ ✓ 509 590
Atto 565 ✓ ✓ ✓ 564 590
Rox ✓ ✓ ✓ 578 604
Texas Red® ✓ ✓ ✓ 590 615
Atto 590 ✓ ✓ ✓ 593 622
Atto Rho13 ✓ ✓ ✓ 603 627
DY480XL ✓ ✓ ✓ 500 630
Atto Rho14 ✓ ✓ ✓ 626 646
Atto 633 ✓ ✓ ✓ 630 651
Atto 647N ✓ ✓ ✓ 646 664
Cy5 ✓ ✓ ✓ 649 670
Atto 665 ✓ ✓ ✓ 662 680
Atto 490LS ✓ ✓ ✓ 495 658
Atto 655 ✓ ✓ ✓ 663 680
Cy5.5 ✓ ✓ ✓ 683 703

Should you not find the fluorescent modification you desire, you can consult the “Alternative dyes” table here, for more information.

Synthesis scales available: 0.02; 0.04; 0.2; 1 µmol.

Purification available: HPLC.

Non-Fluorescent Modifications

Type Position
  5′ 3′ internal
Phosphate ✓ ✓  
C6 Amino ✓    
C12 Amino ✓    
Biotin ✓ ✓ ✓
Biotin-TEG ✓ ✓ ✓
Desthiobiotin-TEG ✓ ✓ ✓
C6 Thiol ✓ ✓ ✓
Digoxigenin ✓ ✓  
Inosine ✓ ✓ ✓
2′ Deoxyuridine ✓ ✓ ✓
5-Me-dC ✓ ✓ ✓
Bromo dG/-dA ✓   ✓
Bromo dC/-dU ✓   ✓
5-Hydroxymethyl-C ✓   ✓
8-oxo-dG ✓   ✓
Alxyl ✓    
AldC ✓ ✓ ✓
AldU ✓ ✓ ✓
Acrydite ✓   ✓
C3-Azid ✓ ✓ ✓
DBCO ✓ ✓ ✓
DBCO-TEG ✓    
C3 spacer ✓ ✓ ✓
C9 spacer ✓ ✓  
HEG spacer ✓ ✓ ✓
Cholesteryl-TEG ✓ ✓  
PC-Amino-Modifier ✓    
PC-Spacer     ✓
Carboxy C10 ✓    
C7 Amino   ✓  
ddC   ✓  
Inverted T   ✓  
Dabcyl   ✓  
MBQ-1   ✓  
MBQ-2   ✓  
BHQ®-1 ✓ ✓  
BHQ®-2 ✓ ✓  
Alrol   ✓  
C2-Amino dT     ✓
C6-Amino dT     ✓
dspacer     ✓
pdC     ✓
pdU     ✓
C3 Thiol   ✓  
C12 spacer     ✓
C6 spacer     ✓
2-Aminopurine     ✓
Atto MB2 ✓ ✓ ✓

For additional information on modifications, please contact us oligo@hylabs.co.il

Please contact us and we will
get back to you shortly

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